The containment discharging system achieves complete operator–material isolation through a triple protection design:

• Glovebox containment chamber allows material handling without direct contact.
• Negative pressure dust extraction captures 100% of airborne dust during charging.
• SS316L stainless steel construction resists pesticide corrosion and extends service life by up to three times.

A dual protection approach combining explosion-proof and inerting systems is applied:

• Explosion-proof design includes ATEX-certified motor and system-wide grounding.
• Oxygen monitoring continuously measures oxygen concentration and automatically initiates nitrogen purging when exceeding 5% LEL.
• Anti-oxidation system nitrogen protection interface maintains oxygen concentration below 1%.
• Closed transfer to reactor prevents air exposure during powder conveying.

The design of dust-free gravimetric filling machine supports seamless process integration with an existing production line.

• Upstream connection: compatible with vibrating feeding stations, pulverizers, and fluid bed dryers to enable a fully automated “unpacking → grinding → drying → packaging” workflow
• Smart control: centralized PLC system with touchscreen interface for parameter settings, fault diagnostics, and production data recording
• Case example: in an inulin production line, integration of wet granulation, extrusion, drying, and dust-free packaging increased overall production efficiency by 40%

It employs a dual-buffer design to maintain continuous operation:

• Inlet buffer chamber allows preloading of 8–12 bottles, functioning like an “ammunition depot” for constant supply.
• Empty bottle storage chamber acts as a “reserve unit,” storing up to 20% backup containers for seamless bottle replacement without process interruption.

The containment isolator system incorporates a three-level dust control strategy:

• Vertical auger filling ensures smooth downward discharge, minimizing dust dispersion.
• Inflatable sealing gate limits powder escape to less than 0.01% during operation.
• Gas circulation system performs up to 15 air exchanges per hour within the chamber, maintaining a clean and stable environment.

This extrusion equipment is designed for pharmaceutical, chemical, and food applications. It processes blended mixtures of powders, excipients, and wet binders into soft, moldable materials. Typical examples include:

• Pharmaceuticals: soft material mixtures, pellet precursors
• Chemicals: catalyst carriers, granular additives
• Food: nutrient enhancers, flavoring bases

Its extrusion system is particularly suitable for continuous production of cylindrical extrudates with high uniformity.

The vertical palletizing extrusion equipment fully complies with GMP and CIP standards:

• Design: modular structure with easy disassembly and polished internal surfaces free of dead corners
• Material: all contact parts made of 316L stainless steel
• Validation: DQ/IQ/OQ documentation templates provided for qualification and verification.

Three major technical advancements distinguish the cooling type extruder:

• Precise temperature control: The extrusion zone maintains a temperature rise of ≤5 °C (with chilled water) or ≤10 °C (with tap water), effectively preventing degradation of heat-sensitive materials.
• Anti-slipping design: The extrusion chamber features a special surface treatment and an adaptive pressure control system, eliminating slippage and material blockage during operation.
• Intelligent monitoring: Real-time temperature monitoring and automatic adjustment of extrusion parameters ensure consistent processing and stable product quality.

It is fully compliant with pharmaceutical manufacturing standards:

• Material: All contact parts are made of 316L stainless steel in accordance with FDA requirements.
• Cleaning: Supports CIP/SIP cleaning with dead-space residue less than 0.01%.
• Documentation: Includes complete IQ/OQ/PQ validation documentation and SAT protocol covering the temperature control module.