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Granulation & Pelletizing Equipment and Systems

Granulation & Pelletizing Equipment and Systems

Vertical Pelletizing Extruder (Cooling Type)

Pharma extruder with an integrated cooling mechanism to handle heat-sensitive materials for pharmaceutical products and drugs

Vertical Pelletizing Extruder (Cooling Type)

The cooling-type vertical pelletizing extruder is an advanced model developed based on the standard vertical design, enhanced with integrated cooling, anti-slipping, and precise temperature control functions. It is engineered for processing temperature-sensitive materials used in pharmaceutical production.

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Specifications
Model CXJ-40 CXJ-80 CXJ-120 CXJ-150 CXJ-200 CXJ-300 CXJ-400
Min. feeding weight 0.15kg 0.3kg 0.5kg 0.5kg 1kg 2kg 2kg
Production capacity (based on Ø 0.8mm) ≤50 ≤80kg/h ≤120kg/h ≤150kg/h ≤260kg/h ≤360kg/h ≤500kg/h
Die aperture Ø0.4–3.0mm Ø0.5–3.0mm Ø0.5–3.0mm Ø0.5–3.0mm Ø0.5–3.0mm Ø0.6–3.0mm Ø0.6–3.0mm
Power supply 380V,50Hz
Rotation speed 5–95rpm
Material return ratio ≥99%
Noise level ＜45dB ＜45dB ＜45dB ＜60dB ＜60dB ＜60dB ＜60dB
Overall dimensions (L×W×H) 86×70×16 cm 95×80×160cm 135×100×162cm 135×110×162cm 150×110×165cm 165×115×165cm 165×120×165cm
Weight 380kg 600kg 800kg 1000kg 1200kg 1500kg 1800kg
Features
  • Efficient temperature control
    The cooling system maintains the extrusion zone within a temperature rise of ≤5 °C (with chilled water) or ≤10 °C (with tap water), ensuring stable operation without heat buildup.
  • Stable material feeding
    The extruder prevents material slippage during processing, maintaining uniform extrusion and consistent product quality.
  • Reliable sealing and easy maintenance
    Equipped with a main inlet and outlet for cooling water, featuring quick-connect couplings for easy setup and disassembly without leakage.
  • Continuous production for heat-sensitive materials
    Enables efficient continuous extrusion for temperature-sensitive compounds, improving productivity and expanding material compatibility.
  • Automated temperature monitoring
    The system continuously measures and regulates the material temperature in real time, ensuring optimal process conditions.
Applications

Ideal for the production of heat-sensitive pharmaceutical pellets and sustained-release formulations such as ibuprofen extended-release micro-pellets, as well as other active pharmaceutical ingredients (APIs) requiring precise temperature control during extrusion.

Compatible Equipment

This extruder is typically paired with a spheronizer to form a complete pelletizing system.
Granulation and Pelletizing Equipment
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Three major technical advancements distinguish the cooling type extruder:

  • Precise temperature control: The extrusion zone maintains a temperature rise of ≤5 °C (with chilled water) or ≤10 °C (with tap water), effectively preventing degradation of heat-sensitive materials.
  • Anti-slipping design: The extrusion chamber features a special surface treatment and an adaptive pressure control system, eliminating slippage and material blockage during operation.
  • Intelligent monitoring: Real-time temperature monitoring and automatic adjustment of extrusion parameters ensure consistent processing and stable product quality.

It is fully compliant with pharmaceutical manufacturing standards:

  • Material: All contact parts are made of 316L stainless steel in accordance with FDA requirements.
  • Cleaning: Supports CIP/SIP cleaning with dead-space residue less than 0.01%.
  • Documentation: Includes complete IQ/OQ/PQ validation documentation and SAT protocol covering the temperature control module.